Malignant Catarrhal Fever
نویسنده
چکیده
Malignant Catarrhal Fever (MCF), a fatal disease of a large number of different ruminants, is caused by infection with either a blue or black wildebeest-associated alcephaline herpesvirus 1 (AlHV-1) or the sheep-associated ovine herpes virus 2 (OvHV-2).Wildebeest and sheep are the natural hosts of these viruses respectively. Both these forms of MCF are of great economic importance, particularly in cattle, but may also cause losses of captive and farmed species of antelope, deer and bison (Bison bison), water buffalo (Bubalus bubalis) and occasionally domestic pigs. Neither of these viruses cause clinical disease in their respective natural hosts (wildebeest and sheep). The clinical course of MCF may vary considerably in individual affected animals – from peracute to acute, chronic or mild. MCF tends to appear sporadically with mostly low morbidity and high mortality rates. However, in some outbreaks, relatively large numbers of animals may be affected.
منابع مشابه
Malignant catarrhal fever in pastoral Maasai herds caused by wildebeest associated alcelaphine herpesvirus-1: An outbreak report
An outbreak of malignant catarrhal fever (MCF), a fatal viral disease in indigenous Tanzanian shorthorn zebu in Ngorongoro district of Tanzania during the period of June 2004 has been described. The disease was diagnosed by clinical, post mortem findings and the virus was identified using molecular characterization study. The history and clinical features included pyrexia, cornel opacity, nasal...
متن کاملAn outbreak of porcine malignant catarrhal fever in a farrow-to-finish swine farm in the United States
Malignant catarrhal fever is a sporadic, often fatal viral disease affecting multiple species, including swine. Ovine herpesvirus type 2 (OvHV-2), the cause of sheep-associated malignant catarrhal fever, incites nonspecific clinical signs and occasional death in swine. An outbreak of malignant catarrhal fever in a farrow-to-finish swine farm in the United States was confirmed by identifying OvH...
متن کاملMalignant catarrhal fever.
Malignant catarrhal fever is briefly reviewed and recent findings are described. Initially the disease was observed as a disease of cattle in Europe where, although no cause could be identified, circumstantial evidence implicated sheep as a source of infection and it was thus designated 'sheep-associated' malignant catarrhal fever. Subsequently the disease was observed in Africa where it became...
متن کاملDevelopment of a multiplex real-time PCR for detection and differentiation of malignant catarrhal fever viruses in clinical samples.
A multiplex real-time PCR was developed using a single pair of primers and fluorescent probes specific for five malignant catarrhal fever viruses and an internal positive control. The assay was able to simultaneously detect and differentiate the viruses in clinical samples with high sensitivity (97.2%) and specificity (100%).
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